

Introduction of PI

Dr. Yi Eve Sun is a leading scientist in neural stem cell biology, neural repair, and autism spectrum disorders. She is a Chair Professor and Principal Investigator at the Shenzhen University of Advanced Technology (SUAT), a Foreign Full Member of the Russian Academy of Engineering (RAE), and a full member of the European Academy of Natural Sciences (EANS). She also serves as Executive Director of the Chinese National Base for International Collaboration on Stem Cells and Regenerative Medicine, and as Deputy Director of the Key Laboratory for Viral Vector Technology Research and Evaluation of Cell and Gene Therapy Products under the Chinese National Medical Products Administration. Previously, she was a tenured professor at University of California, Los Angeles (UCLA) and Associate Academic Director of its Stem Cell Institute. Her groundbreaking research includes studying MECP2 gene function in neural stem cells and establishing disease models for Rett syndrome. She was the first to use gene-editing to create non-human primate models of Rett syndrome, publishing in Cell Stem Cell and Cell. She also identified CD133-positive ependymal cells as key for neural regeneration (Cell). Her research extends to gut microbiota and immune system interactions in central nervous system (CNS) diseases and reprogramming dermal fibroblasts into rejuvenated mesenchymal stem cell-like “Prometheus Cells”, for treating ALS and aging. Dr. Sun has published over 140 papers, including in Cell, Nature, and Science, with more than 20,000 citations and an H-index of 68. She has received numerous awards, including the Alfred P. Sloan Research Fellowship, Beckman Young Investigator Award, and Shanghai Science and Technology Awards, and serves on key scientific boards.
Research Area
CNS Neural Repair via Stem Cells: Systems Biology-based Approaches